{"id":497956,"date":"2026-01-17T15:44:33","date_gmt":"2026-01-17T19:44:33","guid":{"rendered":"https:\/\/deultimominuto.net\/en\/uncategorized\/clinical-trial-shows-advances-in-preventive-vaccine-against-hereditary-cancer\/"},"modified":"2026-01-17T15:44:33","modified_gmt":"2026-01-17T19:44:33","slug":"clinical-trial-shows-advances-in-preventive-vaccine-against-hereditary-cancer","status":"publish","type":"post","link":"https:\/\/deultimominuto.com\/en\/dominican-news\/health\/clinical-trial-shows-advances-in-preventive-vaccine-against-hereditary-cancer\/","title":{"rendered":"Clinical trial shows advances in preventive vaccine against hereditary cancer"},"content":{"rendered":"A clinical trial with the preventive vaccine <strong>NOUS-209<\/strong> has shown encouraging results by achieving an effective stimulation of the immune response in people with <strong>Lynch syndrome<\/strong>, a genetic condition that considerably increases the risk of developing different types of cancer, especially colon and endometrial cancer.\n\nAccording to the biotech company <strong>Nouscom<\/strong>, responsible for the development of the vaccine, NOUS-209 is an immunotherapy designed to activate the T cells of the immune system against <strong>neoantigens<\/strong> present in tumors and precancerous lesions associated with microsatellite instability, a characteristic of this hereditary disease.\n\nThe study&#8217;s findings were published in the scientific journal <strong>Nature Medicine<\/strong> and correspond to a phase 1b\/2 clinical trial, in which <strong>45 people carrying Lynch syndrome<\/strong> participated. This genetic condition carries up to an <strong>80% probability of developing colorectal cancer<\/strong>, in addition to increasing the risk of endometrial, ovarian, urothelial cancer and other tumors.\n\n\n<h3 class=\"wp-block-heading\"><strong>You may be interested in&#8230;<\/strong> <a href=\"https:\/\/ab.deultimominuto.net\/nacionales\/salud\/consumir-semillas-de-calabaza\/\" target=\"_blank\" rel=\"noopener\">The proven benefits of consuming pumpkin seeds<\/a><\/h3>\n\n\nResearchers highlight that the results reinforce the vaccine&#8217;s potential as an innovative strategy to <strong>prevent the development of cancer before it appears<\/strong>, opening a new path in the so-called &#8220;cancer interception&#8221; in patients with high genetic risk.","protected":false},"excerpt":{"rendered":"<p>A clinical trial with the preventive vaccine NOUS-209 has shown encouraging results by achieving an effective stimulation of the immune response in people with Lynch syndrome, a genetic condition that considerably increases the risk of developing different types of cancer, especially colon and endometrial cancer. According to the biotech company Nouscom, responsible for the development [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","_members_access_role":[],"_members_access_error":""},"categories":[37165],"tags":[],"class_list":["post-497956","post","type-post","status-publish","format-standard","category-health"],"acf":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/phj1q1-25xy","jetpack_featured_media_url":"","dum_api":{"author_name":"Redacci\u00f3n De \u00daltimo Minuto","author_image":"https:\/\/deultimominuto.com\/wp-content\/uploads\/2025\/02\/cropped-logo-de-ultimo-minuto-96x96.png","categories_name":["Health"],"featured_media_url":null},"_links":{"self":[{"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/posts\/497956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/comments?post=497956"}],"version-history":[{"count":0,"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/posts\/497956\/revisions"}],"wp:attachment":[{"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/media?parent=497956"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/categories?post=497956"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/deultimominuto.com\/en\/wp-json\/wp\/v2\/tags?post=497956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}